The Spring School is organized by Hildegard Büning, ESGCT; DGGT, DZIF and MHH with the help of 

Local Organizers: Francisco Martin, Marién Cobo, Pilar Muñoz y Karim Benabdellah and M José Mora (SETGyC)(GENYO. FPS.UGR).

SETGyC: Ramón Alemany, Gloria Aseguinolaza y Guillermo Guenechea

The Spring school is an intensive three day lecture course initiated by the ESGCT and in particular dedicated to the training of Students and Post-docs. 

Wednesday 5^th April

11:00-13:00. Retos y esperanzas de las terapias avanzadas.  En español para publico general

• Terapia celular: una nueva forma de hacer medicina (Per Anderson)
• La Terapia génica llega a la clínica (Francisco Martín)
• Ingeniería genética: Terapia génica 2.0 (Miguel G. Toscano)
• Situación de las terapias avanzadas en Andalucía (Natividad Cuende)
   

14:00-14:15 Welcome address (Robin Ali)

14:15-15:15 Keynote Speaker. The origin of CRISPR/Cas9 technology (Francis Mojica)

15:15-17:15 Gene-cell therapy tools I: How to modify a cells in vivo or cell culture?
CHAIR: Miguel Garcia Toscano

• Adeno-associated vectors and friends – a brief overview on non-integrative viral vectors (Hildegard Büning)
• Integrative Viral vectors (Guillermo Güenechea)
• Non-viral vectors (Zoltan Ivics)

17:15-17:45 Coffee

17:45-19:15 Gene-cell therapy tools part II: upcoming technologies and safety consideration
CHAIR: Karim benabdellah

• Genome edition (Paula Rio)
• Tissue engineering  (Ander Izeta)

19:30 Welcome reception and activity in Parainfo

Thursday 6^th April

9:00-10:20 Modeling human disease
CHAIR: Pedro Real

• Cellular and animal models of neurodegenerative diseases (Jose Luis Labandeira)
• Human pluripotent stem cells: iPSCs and hESCs (Pedro Real)

10:20-11:40 Gene & Cell Therapy Strategies: Blood disorders.
CHAIR: Pilar Muñoz

• Haematological disorders (Anne Galy)
• Bone Marrow Failure Syndromes (Juan Bueren)

11:40-12:10 Coffee Break

12:10-14:10 Gene & Cell Therapy Strategies: Neurodegenerative diseases
CHAIR: Rosario Sanchez Pernaute

• Gene Therapy of CNS disorders (Nathalie Cartier)
• Cell Therapy of Parkinson disease (Juan José Toledo-Aral)
• Gene Therapy of Retinal degeneration (Robin Ali)

14:10-15:10 Lunch

15:10-16:30 Gene & Cell Therapy Strategies: Inflammatory and cardiovascular diseases
CHAIR: Mario Delgado

• Cardiac Injury (Pilar Sepulveda)
• Inflammatory diseases (Mario Delgado)

16:30-17:00 Coffee Break

17:00-18:20 Gene & Cell Therapy Strategies: skin and infectious diseases
CHAIR: Daniel Bachiller

• Skin disorders (Marcela del Rio)
• Infectious diseases (Daniel Bachiller)
   

18:20 - 19:00 Safety considerations of gene therapy strategies
CHAIR: Guillermo Güenechea

• Safety and efficacy issues of gene therapy vectors: the pharmacodynamics of GT (Christof Von Kalle)

20:30 Dinner

Friday 7^th April

09:00-11:00 Gene &Cell Therapy Strategies: Metabolic and lysosome storage disorders
CHAIR: Gloria Gonzalez Aseguinolaza

• Liver inherited diseases (Gloria Gonzalez Aseguinolaza)
• Lysosome storage disorders (Nicolina Cristina Sorrentino)
• Towards  a Gene Therapy for Neurological and Somatic Mucopolysaccharidosis (Fatima Bosch)

11:00-11:30 Coffee Break

11:30-13:30 Gene & Cell Therapy Strategies: Cancer
CHAIR: Francisco Martin

• Engineered T cells for cancer treatment (Chiara Bonini)
• Virotherapy. Basic concepts (Ramón Alemany)
• Virotherapy, Clinical applications (Manuel Ramirez)

13:30-14:30 Lunch

14:30-16:30 Breaking towards Gene & Cell Therapy
CHAIR: Natividad Cuende

• Translating gene therapy tools to clinical applications (Adrian Thrasher)
• Gene modified HSCs as therapeutic tool (Luigi Naldini)

6th April: 'Meet the Experts' over Dinner €10 

Topic experts including speakers from the meeting will host round-tables in the beautiful setting of
Carmen de los Chapiteles.
Camino del Avellano, 4, Granada.

We will be meeting at the Carmen de los Chapiteles at 8.30 on Thursday April 6th for drinks followed by dinner which will start at 9pm precisely.

You will be able to exchange opinions and get to know some internationally acclaimed scientists in a relaxed environment whilst admiring one of the most breathtaking views in Europe. 

The evening is being subsidised by the Spring School to facilitate networking and building of collaborations, it is imperative to register to ensure you have a place, there will be NO ONSITE registration to this dinner. You will receive an email closer to the time asking you for your interests and specialties so we can seat everyone appropriately!

7th April: Tour of the Alhambra €20 including transport

The Alhambra is one of the jewels of Southern Europe, and the Spring School was able to reserve 50 tickets for entrance on the 7th in the evening after the Spring School finishes. There will be transport from the venue to the Alhambra, and this is included in the price. Participants will needs to make their own way back. It is imperative that you select this option during registration to be able to join, we are not able to offer tickets and transport beyond these 50.

Health Sciences Technology of Park Foundation
Parque Tecnologico de la Salud (PTS)
Nueva Facultad de Medicina (Parada autobus en frente de la Biblioteca de la Facultad de Medicina)
Edificio PARANINFO
Avenida del Conocimiento s/n.
C.P. 18016. Granada. Spain.
Web: www.ptsgranada.com

Download directions here

By public Transportation

For the venue you will have to catch buses SN4 and U3.  SN4 is the one going to the center of town.

Please check out the Public transportation website for more details

There is one hotel near the venue:

- Abades Nevada Palace (10 minutes walk)
CALLE DE LA SULTANA, 3
18008 GRANADA-
Tarifs for us are as follows:
Double room for single use (breakfast included):  65.00€ 
Double room for double use (breakfast included): 70.00€ 
Triple room for triple use (breakfast included) 90.00€ 
Preferred hotel for the students, there are some rooms available for sharing at a very low price if you use the booking code, springschool you should be able to book those if they are still available.

Or if you prefer we can also recommend some hotels in the centre which are on the right bus route for the venue.

Melia Granada (SPEAKER HOTEL)
CALLE ÁNGEL GANIVET, 7
18009 GRANADA 

Hostal La Redonda (Bus U3 to the venue)
CAMINO DE RONDA, 84 2ª planta,
GRANADA

Casa Salvador (Bus SN4 to the venue
CALLE DUENDE, 6,
18005 GRANADA

Oh! My Hotel (Bus SN4 to the venue)
CALLE SAN PEDRO MARTIR, 34,
18009 GRANADA

Granada Old Town Hotel (Bus U3 to the venue)
ANGEL, 8,
18002 GRANADA