

SPRING SCHOOL PROGRAMME
Check the programme regularly for updates
PLEASE NOTE
Portugal is on Western European Time (WET - Same as London) which is one hour behind CET
Tuesday 14 April
15:00-16:00
Registration
16:00-18:30
Workshops (30 students per workshop)
16:00-18:30
Workshop 1: Public Engagement
Ana Carvalho; GeneT
16:00-18:30
Workshop 4: How to write a patent
TBC
16:00-18:30
Workshop 2: How to write a scientific manuscript
Thomas Gallagher, Human Gene Therapy
16:00-18:30
Workshop 5: How to deliver a convincing speech
TBC
16:00-18:30
Workshop 3: How to create a spin-off (Entrepreneurship & how to make the best out of your inventions)
Sheila Mikhail
19:00-22:00
Break the Ice Dinner @ Vila Galé Hotel
Wednesday 15 April
08:30-08:45
Welcome Address
Alberto Auricchio (President, ESGCT)
Luis Pereira de Almeida (President, Spring School)
Hildegard Büning (ESGCT Education & Training)
08:45-09:45
Keynote
INV01: Jude Samulski m34thx
The past, present and future of Gene and Cell Therapy
09:45-10:15
Coffee Break
10:15-12:00
Session 1: Gene therapy tools - what you should know about viral and non-viral vectors, part I
INV02: Axel Schambach, Hannover Medical School
Insights and challenges on how to design retroviral and lentiviral vectors
INV03: Els Verhoeyen, EVIR, INSERM U758, Lyon; C3M, INSERM U1065, Nice
How to improve nature – the next generation of lentiviral vectors
INV04: Hildegard Büning, Hannover Medical School
Adeno-associated virus (AAV) vector system – the unusual career of non-autonomous parvovirus
12:00-13:45
Lunch Break (with Meet the Expert tables)
13:45-19:00
Guided Tour & treasure hunt
(with coffee break included)
Including Joanina Library, Royal Palace, Science Museum (Physics office), Machado de Castro Museum, Old Church, Almedina Arch, Coimbra Downtown, Chiado Building, Mondego River and Ancient Boat, Finish at Dinner Venue (Saint Marcus Palace)
19:00
Dinner and social activity@Quinta das Lágrimas
https://maps.app.goo.gl/MRioufobm1qBetNWA
Thursday 16 April
07:30-08:30
ESGCT Spring School Morning Run - Between Mondego Bridges
09:00-09:45
Keynote
INV05: Alberto Auricchio, TIGEM, Naples
AAV gene therapy from Bench to Bedside
09:45-11:45
Session 2: Gene therapy on the move
INV06: João Nuno Moreira, CNC-UC, CiBB, University of Coimbra
INV07: Virginia Haurigot
INV08: TBC
INV09: Luis Pereira de Almeida, GeneT
GeneT: the Gene Therapy Center of Excellence (from the idea to the tools applied)
11:45-12:15
Coffee Break
12:15-13:45
Session 4: Beyond conventional CRISPR-Cas strategies (15min + 10 QA/each)
INV10: Toni Cathomen, University of Freiburg
Safety first – how to detect and minimize off-target effects
INV11: Angelo Lombardo, SR-Tiget, Milan
Programming gene silencing by epigenome editing.
INV12: Paula Rio, CIEMAT / CIBERER, Madrid
Gene Therapy for Fanconi
13:45-15:15
Lunch Break
15:15-16:45
Session 5: Stem cells and disease models (15min + 10 QA/each)
INV13: Rui Nobre, GeneT
Pre-clinical in MJD
INV14: TBC
INV15: TBC
16:45-17:15
Coffee Break
17:15-19.00
Session 5: Challenges in gene and cell therapy
INV16: Anne Galy, ART-TG - Inserm US35
Immune system: friend or foe in gene therapy
INV17: Gloria Gonzalez-Aseguinolaza, CIMA, University of Navarra, Pamplona
Potential mechanism involved in AAV toxicity
INV18: Shelia Michail,
INV19: Nathalie Cartier-Lacave,
19:30
Social event and dinner Restaurante Tertúlia D'Eventos
Friday 17April
08.30-10.30
Session 7: Novel approaches in fighting cancer
INV19: Bernhard Gentner, Ludwig Institute for Cancer Research, Lausanne
TBC
INV20: Vincenzo Cirillo, University of Helsinki
INV21: TBC
INV22: TBC
10.30-11.00
Coffee Break
11:00-12:45
Session 8: Pre-clinical & clinical gene therapy
INV23: Francisco Martin, Genyo, Granada
TBC
INV24: Juan Bueren, CIEMAT, Madrid
TBC
INV25: Fatima Bosch, UABarcelona
INV26: Špela Miroševič, CTNNB1 Foundation
12:45-13:00
Closing
Alberto Auricchio, Hildegard Büning & Luis Pereira de Almeida